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To my knowledge, David wrote Psalm 143 at a time when he was fleeing from the rebellion of his son Absalom, who had been joined in his uprising against David by David's former advisor Ahithophel. (This was part of the temporal consequence that God had imposed on David because of his adultery with Bathsheba, and his ordering the murder of Bathsheba's husband Uriah the Hittite (2 Samuel 11-12).) In Psalm 143, even under such dire circumstances (and although he would have known that those circumstances were part of a judgment from God), David did not lose his faith in God, but still looked to Him for help, strength, and ultimate deliverance. In the same way, Christians are to look past adverse temporal circumstances. They can do this because they have the assurance of Scripture (Romans 8:28) that God makes ALL things (not just favorable events) work together for good to those who love Him, (which should motivate them to look for that potential good in any situation, rather than concentrating only on misfortunes). They also have the future assurance through faith in Christ of an eternity spent in God's presence, with which any troubles of this present life are not even worth comparing (Romans 8:18), and of which Christ's resurrection is the guarantee.
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