Genesis 22:1 - 24
ESV - 1 After these things God tested Abraham and said to him, "Abraham!" And he said, "Here am I. 2 He said, "Take your son, your only son Isaac, whom you love, and go to the land of Moriah, and offer him there as a burnt offering on one of the mountains of which I shall tell you.
For follow-up discussion and general commentary on the topic. Comments are sorted chronologically.